Morphometric MRI alterations and postoperative seizure control in refractory temporal lobe epilepsy

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Morphometric MRI alterations and postoperative seizure control in refractory temporal lobe epilepsy

Refractory mesial temporal lobe epilepsy (mTLE) is a debilitating condition potentially amenable to resective surgery. However, between 40 and 50% patients continue to experience postoperative seizures. The development of imaging prognostic markers of postoperative seizure outcome is a crucial objective for epilepsy research. In the present study, we performed analyses of preoperative cortical ...

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Postoperative EEG and seizure outcome in temporal lobe epilepsy surgery.

OBJECTIVE To assess the prognostic value of scalp electroencephalogram (EEG) after epilepsy surgery, we investigated whether postoperative EEG abnormalities (interictal epileptiform discharges, IED; interictal slow activity, ISA) were associated with seizure outcome and other patient characteristics after resective surgery in patients with temporal lobe epilepsy (TLE). METHODS Sixty-two patie...

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P8: Temporal Lobe Epilepsy and Mitochondrial Dysfunction

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evaluation of memory in refractory temporal lobe epilepsy

abstract aim and background: evaluation of cognition is fundamental for every comprehensive epilepsy program. we sought to conduct this study to assess memory state of patients with refractory temporal lobe epilepsy before decision for epilepsy surgery. method and materials: in a case-control study, 20 patients with right temporal lobe epilepsy and 20 patients with left temporal lobe epilepsy w...

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Resection extent versus postoperative outcomes of seizure and memory in mesial temporal lobe epilepsy

OBJECTIVES To investigate the effects of the resection of hippocampus and temporal neocortex on postsurgical seizure and memory outcomes in mesial temporal lobe epilepsy (mTLE) patients. METHODS Sixty-eight mTLE patients underwent pre- and postsurgical brain magnetic resonance imaging (MRI). The patients were divided into seizure-free group (SF, N=54) and non-seizure-free group (NSF, N=14). T...

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ژورنال

عنوان ژورنال: Human Brain Mapping

سال: 2015

ISSN: 1065-9471

DOI: 10.1002/hbm.22722